Serum-CK (Total Creatine Kinase)
Formal name: Creatine kinase (CK)
WHAT IS S-CK (TOTAL CREATINE KINASE)?
Creatine kinase which could also be known as creatine phosphokinase or phospho-creatine kinase is an enzyme that is produced by tissues found in the brain, heart and skeletal muscles.
HOW IS IT USED?
s-CK (Total Creatine Kinase) test is used to detect and control damaged muscles; it helps to detect ill/dead muscle which eventually leads to enzyme leakage out of the cells, diagnose Inflammatory myopathies such as polymyositis, dermatomyositis, Infectious myopathies, Dystrophinopathies, Becker muscular dystrophy, Rhabdomyolysis, Drugs-induced myopathies resulting from statins, fibrates, colchicines, antimalarials, and cocaine. Enzymes leak out of their various cells into the bloodstream when the cells are ill or damaged. This test sometimes could be employed to unveil a subsequent heart attack with the help of troponin test. s-CK level is found in traces in the bloodstream but the CK level detected to be beyond normal would aid the doctors to determine the muscle that is damaged.
WHY DO YOU NEED THE TEST?
Abnormal concentration of s-CK (Total Creatine Kinase) in the bloodstream could result in various muscular diseases such as acute renal failure, Duchenne muscular dystrophy or heart attack. If you have once experienced chest pain or presently experiencing it, the test is useful in diagnosing a potential attack. The level of CK in women with X-linked gene are said to be of high concentration for Duchenne muscular dystrophy. Also, myositis which is an autoimmune disease that brings about severe muscle weakness and damage could be diagnosed with CK test.
WHEN IS IT ORDERED?
When you experience severe muscle pain, weakness or your urine is dark. All these are symptoms of suspected muscle damage.
WHAT IS NEEDED FOR THE TEST?
There is no special requirement needed for the test. A blood sample would be collected from a vein. Please, do inform your doctor if you are using any medication or have any form of allergy before going through the test. You should endeavor to refrain from taking substances like drugs that lower cholesterol, steroids, anesthetics, amphotericin B, also from alcohol, cocaine which could alter CK level.
WHAT TO EXPECT DURING THE TEST.
A blood sample would be collected through your vein into a specimen tube using a sterile needle. You could likely feel a sharp pain as the sterile needle goes in but it won’t last long. The blood sample will be labelled, sent to the lab where it will be properly examined.
WHAT DOES THE RESULTS INDICATE?
- CPK-1 occurs primarily in the brain and lungs. Elevated CPK-1 levels could indicate:
- the presence of an injury or bleeding in the brain
- presence of cancerous cell in the brain.
- the damage of lung tissue or a seizure.
- CPK-2 occurs mainly in the heart. A high concentration levels of CPK-2 shows:
- the presence of a heart injury or damage.
- an inflammation of heart muscles caused by virus or a heart attack.
CPK-3 occurs in the skeletal muscle. The level of CPK-3 shows the presence of:
- high use of illegal drug.
- high rate of immobility.
- could also indicates inflammation.
WHAT ELSE SHOULD I KNOW?
It is paramount that you have it in mind that the result varies and it all boils down to the type of condition/injury. Your medical practitioner will inform you of your results and would be the proper person to tell you the treatment method suitable for you.